메뉴 건너뛰기

  • 식품과 식량문제에 관한 체계적, 과학적 접근 방법들과
    이용을 위한 식품공학의 이론과 실제를 연마

식품유전체학 연구실

지도교수이홍진LEE Hong Jin
hongjin@cau.ac.kr

경력 및 수상

2010.03-현재중앙대학교 생명공학대학 식품공학부 식품공학전공 부교수
2010.03-2014.02중앙대학교 생명공학대학 식품공학부 식품공학전공 조교수
2008.07-2010.02Rutgers, The State University of New Jersey, Chemical Biology, 박사후 연구원
2003.09-2008.06Rutgers, The State University of New Jersey, Food Science 박사
2001.01-2003.01LG생명과학, 연구원
수상2013 자연공학계열 우수교육상 수상 (중앙대학교)
2011 자연공학계열 강의평가 우수 교원
2008 AACR-AstraZeneca Scholar-in-Training Award(미국 암학회)
2007 AACR-Aflac, incorporated Scholar-in-Training Award(미국 암학회)
2003 Graduate Study Abroad Scholarship(한국과학재단)

주요 연구 분야

1 Evaluation of health promoting efficacy of dietary factors in food using in vitro cell culture system and in vivo animal system.

2 Determination of the mechanisms of dietary factors in preventing chronic diseases using food genomics.

학부강의

1영양학 (2학년 1학기)
2생리학 (2학년 2학기)
3식품유전체학 (4학년 1학기)

보유 기술 자산

논문
  • Ko J, Bao C, Park HC, Kim M, Choi HK, Kim YS, Lee HJ, β-Thujaplicin modulates estrogen receptor signaling and inhibits proliferation of human breast cancer cells, Biosci Biotech Biochem, 2015 (In press, Corresponding Author)
  • Bao C, Ko J, Park HC, Kim MC, Kim J, Auh JH, Lee HJ, Sulforaphane inghibited tumor necrosis factor-a induced migration and invasion in estrogen receptor negative human breast cancer cells, Food Sci Biotechnol, 2015, 24:347-351 (Corresponding Author)
  • Kim DY, Kim SH, Ahn HM, Lim SR, Oh J, Choi S, Lee HJ, Auh JH, Choi HK, Differentiation of highbush blueberry (Vaccinium corymbosum L.) fruit cultivars by GC-MS-based metabolic profiling. J Korean Soc App Biol Chem. 2015, 58: 21-28
  • Lee J, Kim SK, Namgung H, Jo Y-H, Bao C, Choi H-K, Auh JH, Lee HJ. Ellagic acid identified through metabolomic analysis is an active metabolite in strawberry (Seolhyang) regulating lipopolisaccharide induced inflammation. J Agri Food Chem. 2014, 62: 3954-3962 (Corresponding Author)
  • Bao C, Namgung H, Lee J, Park H-C, Ko J, Moon HJ, Ko HW, Lee HJ. Daidzein Suppresses Tumor Necrosis Factor-a Induced Migration and Invasion by Inhibiting Hedgehog/Gli1 Signaling in Human Breast Cancer Cells. J Agri Food Chem. 2014, 62: 3759-3767 (Corresponding Author)
  • Kown BH, Kim SU, Lim SY, Namgung H, Lee HJ. Determination of Glucose Distribution of Potato Tuber Using Blood Glucose Meter and Its Application to Estimate Processing Quality. Kor J Hort Sci Technol. 2014, 32: 171-177 (Corresponding Author)
  • Jo Y-H, Kim SK, Kwon DA, Lee HJ, Choi HK, Auh JH. Metabolomic Analysis of Ethyl Acetate and Methanol Extracts of Blueberry. J Korean Soc Food Sci Nutr. 2014, 43: 419-424
  • Lee JH, Lee HJ. A Daidzein Metabolite, 6,7,4'-Trihydroxyisoflavone Inhibits Cellular Proliferation through Cell Cycle Arrest and Apoptosis Induction in MCF10CA1a Human Breast Cancer Cells. J Korean Soc App Biol Chem. 2013, 56:695-700 (Corresponding Author)
  • Lee DY, Heo S, Kim SK, Choi H-K, Lee HJ, Cho S-M, Auh J-H. Metabolomic characterization of the region- and maturity-specificity of Rubus coreanus Miquel (Bokbunja). Food Res Int. 2013, 54: 508-515
  • Smolarek AK, So JY, Thomas PE, Lee HJ, Paul S, Dombrowski A, Wang CX, Saw CL, Khor TO, Kong AN, Reuhl K, Lee MJ, Yang CS, Suh N. Dietary tocopherols inhibit cell proliferation, regulate expression of ERα, PPARγ, and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia. Mol Carcinogenesis. 2013, 52: 514-525.
  • Maehr H, Rochel N, Lee, HJ, Suh N, Uskokovic, MR. Diastereotopic and Deuterium Effects in Gemini, J Med Chem. 2013, 56: 3878-3888
  • Suh HW, Park SJ, Hyun SH, Lee SY, Auh JH, Lee HJ, Cho SM, Kim JH, and Choi HK, Effect of black raspberry (Rubus coreanus Miquel) fruit administration on DNA damage levels in smokers and screening biomarker development using 1H-NMR-based metabolic profiling, Food Res Int. 2013, 54: 1255-1262
  • So JY, Lee HJ, Kramata P, Minden A, and Suh N, Differential expression of key signaling proteins in MCF10 cell lines, a human breast cancer progression model. Mol Cell Pharmacol. 2012 4(1):31-40
  • Suh N, Paul S, Lee HJ, Yoon T, Shah N, Son AI, Reddi AH, Medici D, Sporn MB, Synthetic triterpenoids, CDDO-Imidazolide and CDDO-Ethyl amide, induce chondrogenesis. Osteoarthritis and Cartilage, 2012, 20(5):446-50 (First Author, Equal Contribution)
  • Shin JP, Hyun SH, Suh HW, LEE SY, Min TS, Auh JH, Lee HJ, Kim JH, Cho SM, Choi HK, Differentiation of Black Rasberry Fruits According to Species and Geographic Origins by Genomic Analysis and 1H-NMR-based Metabolic Profiling. J Korean Soc Appl Biol Chem. 2012; 55(5):633-642
  • Lee HJ, Vitamin D and Breast Cancer: Molecular Communications. J Korean Soc Appl Biol Chem. 2011; 54(6):841-851 (Corresponding Author)
  • Huet T, Maehr H, Lee HJ, Uskokovic MR, Suh N, Moras D, Rochel N, Structure-function study of gemini derivatives with two different side chains at C-20, Gemini-0072 and Gemini-0097. Medchemcomm. 2011;2(5):424-429
  • Suh N, Reddy BS, Decastro A, Paul S, Lee HJ, Smolarek AK, So JY, Simi B, Wang CX, Janakiram NB, Steele VE, Rao CV. Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/beta-catenin/cyclin D1 signaling pathway in rat. Cancer Prev Res, 2011; 4(11): 1895-1902
  • Heo S, Lee DY, Choi HK, Lee J, Lim JH, Cho SM, Lee HJ, Auh JH., Metabolite Fingerprinting of Bokbunja (Rubus coreanus Miquel) by UPLC-qTOF-MS, Food Sci Biotechnol, 2011, 20(2): 567-570.
  • So JY, Lee HJ, Smolarek AK, Paul S, Wang CX, Maehr H, Uskokovic M, Zheng X, Conney AH, Cai L, Liu F, Suh N., A Novel Gemini Vitamin D Analog Represses the Expression of a Stem Cell Marker CD44 in Breast Cancer. Mol Pharmacol. 2011;79(3):360-7 (First Author, Equal contribution)
  • Paul, S., Mizuno, C.S., Lee, H.J., Zheng, X., Chajkowisk, S., Rimoldi, J.M., Conney, A., Suh, N., Rimando, A.M. In vitro and in vivo studies on stilbene analogs as potential treatment agents for colon cancer. Eur J Med Chem. 2010:45(9):3702-3708.
  • Lee, H.J., So, J.Y., Decastro, A., Smolarek, A., Paul, S., Maehr, H., Uskokovic, M., Suh, N. Gemini vitamin D analog suppresses ErbB2-positive mammary tumor growth via inhibition of ErbB2/AKT/ERK signaling. J Steroid Biochem Mol Biol 121: 408-412, 2010 (First Author)
  • Paul, S., Decastro, A., Lee, H.J., Smolarek, A.K., So, J.Y., Simi, B., Wang, C.X., Zhou, R., Rimando, A.M., Suh, N. Dietary intake of pterostilbene, a constituent of blueberries, inhibits the {beta}-catenin/p65 downstream signaling pathway and colon carcinogenesis in rats. Carcinogenesis 31: 1272-1278, 2010
특허
  • 오디 유래 색소 추출물을 유효성분으로 함유하는 항염증 조성물 (2015년 1월 등록)
  • 복분자 유래 색소 추출물을 유효성분으로 함유하는 항염증 조성물 (2015년 1월 등록)
저서 및 역서
  • Lee, H.J. and Suh, N., "Vitamin E and cancer prevention," in Chemoprevention of Cancer and DNA Damage by Dietary Factors, Edited by Siegfried Knasmuller, David M. DeMarini, Ian Johnson, and Clarissa Gerhauser, Wiley-VCH, Verlag CmbH & Co. KGaA, Weinheim, p402-415, 2009.
  • 이형주, 장해동, 이기원, 이홍진, 강남주., 기능성식품학, 수학사, 2011
위로